"Reactive Oxygen Species: Advances and Developments" ed. by Rizwan Ahmad, Andrei Surguchov

This volume is a comprehensive book that delves into the intricacies of Reactive Oxygen Species (ROS). It provides invaluable insights to researchers in the field, equipping them with the essential tools and knowledge to advance their work in this critical area, leading to the development of novel therapeutic interventions to manage various illnesses.

Reactive Oxygen Species (ROS) are molecules generated naturally during cellular metabolic processes. They act as signaling agents that oversee specific biochemical pathways, playing a vital role in cell function and survival. However, an imbalance in ROS signaling or excessive ROS production can have harmful effects on the pathophysiology of diseases. ROS are crucial to cell signaling and are involved in various physiological processes. They modulate gene expression, regulate cell cycle progression, and influence immune responses. Although ROS are essential for normal cellular functions, an overabundance of these molecules can lead to oxidative stress, causing DNA damage, lipid peroxidation, and protein oxidation, adversely impacting cell function and leading to various diseases. Therefore, it is critical to regulate ROS levels precisely to maintain cellular homeostasis.

Contents
1. Reactive Oxygen Species – Origin and Significance
2. Reactivity and Applications of Singlet Oxygen Molecule
3. Relevance of Oxidoreductases in Cellular Metabolism and Defence
4. The Good and the Bad: The Bifunctional Enzyme Xanthine Oxidoreductase in the Production of Reactive Oxygen Species
5. Methylmercury Promotes Oxidative Stress and Activation of Matrix Metalloproteinases: Cardiovascular Implications
6. Oxidative Stress and Reproduction Health: Physiology, Pathology, and Clinical Biomarkers
7. Oxidative Stress and Male Fertility: Promising Role of Nutraceuticals
8. Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling Pathways and Nano-Particles as Carriers


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